A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis

Study Purpose

This phase III study will evaluate the efficacy, safety and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) compared with placebo in participants with idiopathic pulmonary fibrosis (IPF).

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

No
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Interventional
Eligible Ages 40 Years - 85 Years
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

  • - Documented diagnosis of IPF per the 2018 American Thoracic Society (ATS)/European Respiratory Society (ERS)/Japanese Respiratory Society (JRS)/Latin American Thoracic Society (ALAT) Clinical Practice Guideline.
  • - High-resolution computed tomography (HRCT) pattern consistent with the diagnosis of IPF, confirmed by central review of Chest HRCT and central review of any available lung biopsy (LB) - Minimum 6 minute walk distance (6MWD) of 150 meters with maximum use of 6 L/min at sea-level and up-to 8 L/min at altitude of supplemental oxygen while maintaining oxygen saturation of greater than or equal to (>/= )83% during the 6 minute walk test (6MWT) during screening.
  • - FVC >/= 45% predicted during screening.
  • - Forced expiratory volume in 1 second (FEV1)/FVC ratio greater than (>) 0.70 during screening.
  • - Diffusing capacity for carbon monoxide (DLCO) >/= 30% and less than or equal to (
  • - If receiving pirfenidone or nintedanib treatment for IPF, the patient must have been on treatment for at least 3 months and a stable dose for at least 4 weeks prior to screening, and during screening.
  • - If not currently receiving nintedanib or pirfenidone treatment (either treatment naïve or having previously taken and discontinued) must have discontinued such treatment >/= 4 weeks prior to screening and during screening.
  • - Anticipated life expectancy of at least 12 months at baseline.
  • - Patient and investigator considered all medicinal treatment options and/or possibly lung transplantation prior to considering participation in the study.

Exclusion Criteria:

  • - Evidence of other known causes of Interstitial Lung Disease (ILD) - FVC% predicted value showing repeated increase in the 6 months period prior to screening and including screening value.
  • - Emphysema present on greater than or equal to (>/=) 50% of the HRCT, or the extent of emphysema is greater than the extent of fibrosis, according to central review of the HRCT.
  • - Receiving nintedanib in combination with pirfenidone.
  • - Received cytotoxic, immunosuppressive, cytokine modulating, or receptor antagonist agents (including but not limited to methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, cyclosporine or other steroid sparing agent) within 4 weeks of screening.
  • - Receiving systemic corticosteroids equivalent to prednisone > 10 mg/day or equivalent within 2 weeks prior to screening.
  • - Acute respiratory or systemic bacterial, viral, or fungal infection either during screening or prior to screening and not successfully resolved 4 weeks prior to screening visit.
  • - Participants with active or latent tuberculosis (confirmed within the 6 months prior to or during screening, by a positive screening test [interferon gamma release assay]) - Resting oxygen saturation of < 89% using up to 4 L/min of supplemental oxygen at sea level and up to 6 L/min at altitude (>/= 5000 feet [1524 meters] above sea level) during screening.
  • - Class IV New York Heart Association chronic heart failure.
  • - Historical evidence of left ventricular ejection fraction < 35% - Presence of pulmonary hypertension that, in the investigator's opinion, would substantially limit the ability to comply with study requirements or may influence any of the safety or efficacy assessments included in the study.
  • - Cardiopulmonary rehabilitation program based on exercise training that has been completed within 8 weeks prior to screening or planned to start during the patient's enrollment in this trial.
  • - History of smoking, alcohol or substance abuse disorder, or a malignancy.
  • - Previous treatment with PRM-151.
- Clinically significant abnormality on ECG during screening including prolonged corrected QT interval > 450 ms (for men) or > 470 ms (for women) based on the Fridericia correction formula; or laboratory tests (hematology, serum chemistry, and urinalysis) that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT04552899
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Phase 3
Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Hoffmann-La Roche
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Clinical Trials
Principal Investigator Affiliation Hoffmann-La Roche
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Industry
Overall Status Recruiting
Countries Argentina, Australia, Austria, Belgium, Brazil, Canada, China, Czechia, Denmark, Finland, France, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Korea, Republic of, Mexico, Netherlands, New Zealand, Norway, Peru, Poland, Portugal, Russian Federation, Singapore, South Africa, Spain, Sweden, Switzerland, Taiwan, Turkey, Ukraine, United Kingdom, United States
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Idiopathic Pulmonary Fibrosis
Arms & Interventions

Arms

Experimental: PRM-151

Participants will receive intravenous (IV) infusions of PRM-151 over 50-70 minutes on Days 1, 3 and 5, then followed by infusions every 4 weeks (Q4W) to Week 48.

Placebo Comparator: Placebo

Participants will receive IV infusions of placebo over 50-70 minutes on Days 1, 3 and 5, followed by infusions Q4W to Week 48.

Interventions

Drug: - PRM-151

A 10 mg/kg IV infusion of PRM-151 based on the participants weight will be administered on Days 1, 3 and 5 followed by infusions Q4W to Week 48.

Drug: - Placebo

Placebo matching PRM-151 will be administered by IV infusion on Days 1, 3 and 5, followed by infusions Q4W to Week 48.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

University of Alabama at Birmingham, Birmingham, Alabama

Status

Not yet recruiting

Address

University of Alabama at Birmingham

Birmingham, Alabama, 35294

Phoenix, Arizona

Status

Not yet recruiting

Address

Banner University Medical Center Phoenix; Main Pharmacy

Phoenix, Arizona, 85006

Lovelace Scientific Resources, Inc., Phoenix, Arizona

Status

Not yet recruiting

Address

Lovelace Scientific Resources, Inc.

Phoenix, Arizona, 85016

VA Long Beach Healthcare System, Long Beach, California

Status

Not yet recruiting

Address

VA Long Beach Healthcare System

Long Beach, California, 90822

Los Angeles, California

Status

Not yet recruiting

Address

Keck School of Medicine - University of Southern California

Los Angeles, California, 90033

Los Angeles, California

Status

Not yet recruiting

Address

University of California Los Angeles Medical Center

Los Angeles, California, 90095

University of California Davis, Sacramento, California

Status

Not yet recruiting

Address

University of California Davis

Sacramento, California, 95817

Inst. of Healthcare Assessment, Inc., San Diego, California

Status

Not yet recruiting

Address

Inst. of Healthcare Assessment, Inc.

San Diego, California, 92120

Sutter Health, San Francisco, California

Status

Not yet recruiting

Address

Sutter Health

San Francisco, California, 94109

UCSF Medical Center, San Francisco, California

Status

Not yet recruiting

Address

UCSF Medical Center

San Francisco, California, 94143-0748

Paloma Medical Group, San Juan Capistrano, California

Status

Not yet recruiting

Address

Paloma Medical Group

San Juan Capistrano, California, 92675

William Sansum Diabetes Center, Santa Barbara, California

Status

Not yet recruiting

Address

William Sansum Diabetes Center

Santa Barbara, California, 93105

Standford Hosp, Stanford, California

Status

Not yet recruiting

Address

Standford Hosp

Stanford, California, 94305

West Hollywood, California

Status

Not yet recruiting

Address

Cedars-Sinai Medical Center (CSMC) - Women's Guild Lung Institute

West Hollywood, California, 90048-1804

National Jewish Health Medical Center, Denver, Colorado

Status

Not yet recruiting

Address

National Jewish Health Medical Center

Denver, Colorado, 80045-2541

Yale New Haven Hospital, New Haven, Connecticut

Status

Not yet recruiting

Address

Yale New Haven Hospital

New Haven, Connecticut, 06510

Newark, Delaware

Status

Not yet recruiting

Address

Christiana Care Pulmonary Associates - Newark

Newark, Delaware, 19713-2074

Georgetown University Medical Center, Washington, District of Columbia

Status

Not yet recruiting

Address

Georgetown University Medical Center

Washington, District of Columbia, 20007

Meris Clinical Research, Brandon, Florida

Status

Not yet recruiting

Address

Meris Clinical Research

Brandon, Florida, 33511-5719

Celebration, Florida

Status

Not yet recruiting

Address

Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration

Celebration, Florida, 34747-1818

Daytona Beach, Florida

Status

Not yet recruiting

Address

Advanced Pulmonary & Sleep Research Institute of Florida

Daytona Beach, Florida, 32117

Jacksonville, Florida

Status

Not yet recruiting

Address

University of Florida Health Pulmonology - Jacksonville

Jacksonville, Florida, 32209

San Marcus Research Clinic Inc., Miami, Florida

Status

Not yet recruiting

Address

San Marcus Research Clinic Inc.

Miami, Florida, 33015

Renstar Medical Research, Ocala, Florida

Status

Not yet recruiting

Address

Renstar Medical Research

Ocala, Florida, 34470

Central Florida Pulmonary Group, PA, Orlando, Florida

Status

Recruiting

Address

Central Florida Pulmonary Group, PA

Orlando, Florida, 32803

Sarasota County Public Hospital, Sarasota, Florida

Status

Not yet recruiting

Address

Sarasota County Public Hospital

Sarasota, Florida, 34239

University of South Florida, Tampa, Florida

Status

Not yet recruiting

Address

University of South Florida

Tampa, Florida, 33612

Clinovation Research, Weston, Florida

Status

Not yet recruiting

Address

Clinovation Research

Weston, Florida, 33327

Clinical Site Partners Orlando, Winter Park, Florida

Status

Not yet recruiting

Address

Clinical Site Partners Orlando

Winter Park, Florida, 32789

Emory University, Atlanta, Georgia

Status

Not yet recruiting

Address

Emory University

Atlanta, Georgia, 30322

Austell, Georgia

Status

Not yet recruiting

Address

Piedmont Healthcare Pulmonary and Critical Care Research

Austell, Georgia, 30106

Rush University Medical Center, Chicago, Illinois

Status

Not yet recruiting

Address

Rush University Medical Center

Chicago, Illinois, 60612

University of Chicago Medical Center, Chicago, Illinois

Status

Not yet recruiting

Address

University of Chicago Medical Center

Chicago, Illinois, 60637

NorthShore University HealthSystem, Evanston, Illinois

Status

Not yet recruiting

Address

NorthShore University HealthSystem

Evanston, Illinois, 60201

Maywood, Illinois

Status

Not yet recruiting

Address

Loyola University Medical Center; Clinical Trials Pharmacy

Maywood, Illinois, 60153

Indiana Univ School of Med, Indianapolis, Indiana

Status

Not yet recruiting

Address

Indiana Univ School of Med

Indianapolis, Indiana, 46202

Iowa City, Iowa

Status

Not yet recruiting

Address

University of Iowa Hospitals and Clinics; Investigational Drug Services

Iowa City, Iowa, 52242

University of Kansas Medical Center, Kansas City, Kansas

Status

Not yet recruiting

Address

University of Kansas Medical Center

Kansas City, Kansas, 66160

Lexington, Kentucky

Status

Not yet recruiting

Address

University of Kentucky Albert B. Chandler Hospital - Pavilion H

Lexington, Kentucky, 40536

Louisville, Kentucky

Status

Not yet recruiting

Address

University of Louisville Health Sciences Center

Louisville, Kentucky, 40202

Tulane University School of Medicine, New Orleans, Louisiana

Status

Not yet recruiting

Address

Tulane University School of Medicine

New Orleans, Louisiana, 70112-2600

Massachusetts General Hospital, Boston, Massachusetts

Status

Not yet recruiting

Address

Massachusetts General Hospital

Boston, Massachusetts, 02114

Beth Israel Deaconess Med Ctr, Boston, Massachusetts

Status

Not yet recruiting

Address

Beth Israel Deaconess Med Ctr

Boston, Massachusetts, 02215

University of Minnesota Medical Center, Minneapolis, Minnesota

Status

Not yet recruiting

Address

University of Minnesota Medical Center

Minneapolis, Minnesota, 29425-8911

Mayo Clinic Rochester, Rochester, Minnesota

Status

Not yet recruiting

Address

Mayo Clinic Rochester

Rochester, Minnesota, 55902

The Lung Research Center, Chesterfield, Missouri

Status

Not yet recruiting

Address

The Lung Research Center

Chesterfield, Missouri, 63017-3625

Washington University, Saint Louis, Missouri

Status

Not yet recruiting

Address

Washington University

Saint Louis, Missouri, 63128

University of Nebraska Medical Center, Omaha, Nebraska

Status

Not yet recruiting

Address

University of Nebraska Medical Center

Omaha, Nebraska, 68198-0600

Lebanon, New Hampshire

Status

Not yet recruiting

Address

Dartmouth-Hitchcock Medical Center ; Pulmonary/Clinic 5C

Lebanon, New Hampshire, 03756

Pulmonary & Allergy Associates, Summit, New Jersey

Status

Not yet recruiting

Address

Pulmonary & Allergy Associates

Summit, New Jersey, 07901-4055

Albany Med College, Albany, New York

Status

Not yet recruiting

Address

Albany Med College

Albany, New York, 12208

Stony Brook Internists PC, Commack, New York

Status

Not yet recruiting

Address

Stony Brook Internists PC

Commack, New York, 11725-5020

Icahn School of Medicine at Mount Sinai, New York, New York

Status

Not yet recruiting

Address

Icahn School of Medicine at Mount Sinai

New York, New York, 10029

Lenox Hill Hospital, New York, New York

Status

Not yet recruiting

Address

Lenox Hill Hospital

New York, New York, 10075

American Health Research Inc., Charlotte, North Carolina

Status

Not yet recruiting

Address

American Health Research Inc.

Charlotte, North Carolina, 28277

Duke University Medical Center, Durham, North Carolina

Status

Not yet recruiting

Address

Duke University Medical Center

Durham, North Carolina, 27710

Pulmonix Research, Greensboro, North Carolina

Status

Not yet recruiting

Address

Pulmonix Research

Greensboro, North Carolina, 27403-1127

PMG Research of Wilmington, Wilmington, North Carolina

Status

Not yet recruiting

Address

PMG Research of Wilmington

Wilmington, North Carolina, 28401

Cincinnati, Ohio

Status

Not yet recruiting

Address

University of Cincinnati; Department of Psychiatry and Behavioral Neuroscience

Cincinnati, Ohio, 45219

Cleveland, Ohio

Status

Not yet recruiting

Address

University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44016

Cleveland Clinic, Cleveland, Ohio

Status

Not yet recruiting

Address

Cleveland Clinic

Cleveland, Ohio, 44195

Columbus, Ohio

Status

Not yet recruiting

Address

The Ohio State University Wexner Medical Center

Columbus, Ohio, 43212

Mercy St. Vincent Medical Center, Toledo, Ohio

Status

Not yet recruiting

Address

Mercy St. Vincent Medical Center

Toledo, Ohio, 43608

Oregon Health and Science University, Portland, Oregon

Status

Not yet recruiting

Address

Oregon Health and Science University

Portland, Oregon, 97239

Philadelphia, Pennsylvania

Status

Not yet recruiting

Address

Jefferson University Physicians (JUP) - Jefferson Pulmonary

Philadelphia, Pennsylvania, 19107

Temple University Medical Center, Philadelphia, Pennsylvania

Status

Not yet recruiting

Address

Temple University Medical Center

Philadelphia, Pennsylvania, 19140-4105

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Status

Not yet recruiting

Address

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213

Charleston, South Carolina

Status

Not yet recruiting

Address

Medical University of South Carolina Hospital

Charleston, South Carolina, 29425

SleepMed of South Carolina, Columbia, South Carolina

Status

Not yet recruiting

Address

SleepMed of South Carolina

Columbia, South Carolina, 29201-2953

Greenville Pharmaceutical Research, Greenville, South Carolina

Status

Withdrawn

Address

Greenville Pharmaceutical Research

Greenville, South Carolina, 29615

Lowcountry Lung and Critical Care, North Charleston, South Carolina

Status

Recruiting

Address

Lowcountry Lung and Critical Care

North Charleston, South Carolina, 29406

Carolina Lung Clinic, PA, Rock Hill, South Carolina

Status

Not yet recruiting

Address

Carolina Lung Clinic, PA

Rock Hill, South Carolina, 29732

Spartanburg Regional Medical Center, Spartanburg, South Carolina

Status

Not yet recruiting

Address

Spartanburg Regional Medical Center

Spartanburg, South Carolina, 29303

VitaLink Research - Spartanburg, Spartanburg, South Carolina

Status

Not yet recruiting

Address

VitaLink Research - Spartanburg

Spartanburg, South Carolina, 29303

Vanderbilt University Medical Center, Nashville, Tennessee

Status

Not yet recruiting

Address

Vanderbilt University Medical Center

Nashville, Tennessee, 37232

Horizon Clinical Research Group, Cypress, Texas

Status

Not yet recruiting

Address

Horizon Clinical Research Group

Cypress, Texas, 77429

Dallas, Texas

Status

Not yet recruiting

Address

University of Texas Southwestern Medical Center; Pediatrics

Dallas, Texas, 75235

Galveston, Texas

Status

Not yet recruiting

Address

University of Texas Medical Branch; Cardiology Department

Galveston, Texas, 77555

Metroplex Pulmonology & Sleep Center, McKinney, Texas

Status

Not yet recruiting

Address

Metroplex Pulmonology & Sleep Center

McKinney, Texas, 75069

San Antonio, Texas

Status

Not yet recruiting

Address

University of Texas Health Sciences Center in San Antonio

San Antonio, Texas, 78229

Salt Lake City, Utah

Status

Not yet recruiting

Address

University Of Utah Hosp & Clin; Investigational Pharmacy

Salt Lake City, Utah, 84132

Inova Fairfax Hospital/IHVI; Cardiology, Falls Church, Virginia

Status

Not yet recruiting

Address

Inova Fairfax Hospital/IHVI; Cardiology

Falls Church, Virginia, 22042

Virginia Commonwealth University, Richmond, Virginia

Status

Not yet recruiting

Address

Virginia Commonwealth University

Richmond, Virginia, 23292

University of Washington Medical Center, Seattle, Washington

Status

Not yet recruiting

Address

University of Washington Medical Center

Seattle, Washington, 98195

University of Wisconsin-Madison, Madison, Wisconsin

Status

Not yet recruiting

Address

University of Wisconsin-Madison

Madison, Wisconsin, 53792

Medical College of Wisconsin, Milwaukee, Wisconsin

Status

Not yet recruiting

Address

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226

International Sites

Fundacion Favaloro, Buenos Aires, Argentina

Status

Not yet recruiting

Address

Fundacion Favaloro

Buenos Aires, , C1093AAS

Buenos Aires, Argentina

Status

Not yet recruiting

Address

Centro de Alergia y Enfermedades Respiratorias

Buenos Aires, ,

Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, Argentina

Status

Not yet recruiting

Address

Hospital Britanico de Buenos Aires

Ciudad Autonoma Buenos Aires, , C1284AEB

Ciudad Autonoma Buenos Aires, Argentina

Status

Not yet recruiting

Address

Fundacion Respirar (Centro Medico Dra. De Salvo)

Ciudad Autonoma Buenos Aires, , C1426ABP

Córdoba, Argentina

Status

Not yet recruiting

Address

Instituto de Medicina Respiratoria, IMeR; Clinic/Outpatient Facility

Córdoba, , X5003DCE

Florida, Argentina

Status

Not yet recruiting

Address

Centro Medico de Enfermedades Respiratorias (CEMER)

Florida, ,

Centro de estudios respiratorios, Mar del Plata, Argentina

Status

Not yet recruiting

Address

Centro de estudios respiratorios

Mar del Plata, ,

INSARES, Mendoza, Mendoza City, Argentina

Status

Not yet recruiting

Address

INSARES

Mendoza, Mendoza City, , M5500CCG

Fundación Scherbovsky, Mendoza, Argentina

Status

Not yet recruiting

Address

Fundación Scherbovsky

Mendoza, , 5500

Centro Respiratorio Infantil, Rosario, Argentina

Status

Not yet recruiting

Address

Centro Respiratorio Infantil

Rosario, , 2000

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

Status

Not yet recruiting

Address

Royal Prince Alfred Hospital

Camperdown, New South Wales, 2050

Liverpool, New South Wales, Australia

Status

Not yet recruiting

Address

South Western Sydney Local Health District - Eastern Campus Liverpool Hospital

Liverpool, New South Wales, 1871

Lung Research Queensland, Nundah, Queensland, Australia

Status

Not yet recruiting

Address

Lung Research Queensland

Nundah, Queensland, 4101

Mater Medical Centre - Brisbane, South Brisbane, Queensland, Australia

Status

Not yet recruiting

Address

Mater Medical Centre - Brisbane

South Brisbane, Queensland, 4101

Princess Alexandra Hospital, Woolloongabba, Queensland, Australia

Status

Not yet recruiting

Address

Princess Alexandra Hospital

Woolloongabba, Queensland, 4102

The Queen Elizabeth Hospital, Adelaide, South Australia, Australia

Status

Not yet recruiting

Address

The Queen Elizabeth Hospital

Adelaide, South Australia, 5011

The Alfred Hospital, Prahan, Victoria, Australia

Status

Not yet recruiting

Address

The Alfred Hospital

Prahan, Victoria, 3181

Fiona Stanley Hospital, Murdoch, Western Australia, Australia

Status

Not yet recruiting

Address

Fiona Stanley Hospital

Murdoch, Western Australia, 6150

St John of God Hospital, Murdoch, Western Australia, Australia

Status

Not yet recruiting

Address

St John of God Hospital

Murdoch, Western Australia, WA6150

Nedlands, Western Australia, Australia

Status

Not yet recruiting

Address

Sir Charles Gairdner Hospital; Department Of Respirtory Medicine, WA Lung Reserch

Nedlands, Western Australia, 6009

Graz, Austria

Status

Not yet recruiting

Address

LKH - Universitätklinikum Graz; Universitätsklinik für Kardiologie

Graz, , 8036

Innsbruck, Austria

Status

Not yet recruiting

Address

Medizinische Universitaet Innsbruck - Universitaetsklinik fuer Innere Medizin III

Innsbruck, , 6020

Klagenfurt, Austria

Status

Not yet recruiting

Address

Klinikum Klagenfurt am Wörthersee; 2. Medizinische Abteilung

Klagenfurt, , 9020

Salzburg, Austria

Status

Not yet recruiting

Address

Landeskrankenhaus Salzburg; Gynäkologie Und Onkologie

Salzburg, , 5020

Vienna, Austria

Status

Not yet recruiting

Address

AKH - Medizinische Universität Wien; Department of Oncology

Vienna, , 1090

ULB Hôpital Erasme, Brussels, Belgium

Status

Not yet recruiting

Address

ULB Hôpital Erasme

Brussels, , 1070

Universitair Ziekenhuis Brussel, Brussels, Belgium

Status

Not yet recruiting

Address

Universitair Ziekenhuis Brussel

Brussels, , 1090

Bruxelles, Belgium

Status

Not yet recruiting

Address

Cliniques Universitaires Saint-Luc; Pharmacy

Bruxelles, , 1200

UZ Leuven, Leuven, Belgium

Status

Not yet recruiting

Address

UZ Leuven

Leuven, , 3000

C. H. U. Sart-Tilman; Laboratory, Liège, Belgium

Status

Not yet recruiting

Address

C. H. U. Sart-Tilman; Laboratory

Liège, , 4000

CHU UCL Namur / site Godinne, Yvoir, Belgium

Status

Not yet recruiting

Address

CHU UCL Namur / site Godinne

Yvoir, , B5530

Salvador, BA, Brazil

Status

Not yet recruiting

Address

Núcleo de Estudos Clínicos da Bahia Hospital Universitário Professor Edgard Santos

Salvador, BA, 40110-060

Belo Horizonte, MG, Brazil

Status

Not yet recruiting

Address

Hospital das Clínicas da Universidade Federal do Paraná - HCPR

Belo Horizonte, MG, 30130-100

Hospital Madre Tereza, Belo Horizonte, MG, Brazil

Status

Not yet recruiting

Address

Hospital Madre Tereza

Belo Horizonte, MG, 30441-070

Porto Alegre, RS, Brazil

Status

Not yet recruiting

Address

Santa Casa de Misericordia de Porto Alegre

Porto Alegre, RS, 90050-170

Hospital Ernesto Dornelles, Porto Alegre, RS, Brazil

Status

Not yet recruiting

Address

Hospital Ernesto Dornelles

Porto Alegre, RS, 90160-092

Hospital Sao Lucas da PUCRS*X, Porto Alegre, RS, Brazil

Status

Not yet recruiting

Address

Hospital Sao Lucas da PUCRS*X

Porto Alegre, RS, 90610-000

Hospital Dia do Pulmão, Blumenau, SC, Brazil

Status

Not yet recruiting

Address

Hospital Dia do Pulmão

Blumenau, SC, 89030-101

Faculdade de Medicina do ABC - FMABC, Santo Andre, SP, Brazil

Status

Not yet recruiting

Address

Faculdade de Medicina do ABC - FMABC

Santo Andre, SP, 09060-650

Sao Paulo, SP, Brazil

Status

Not yet recruiting

Address

*X*Hospital das Clinicas - FMUSP; Hematologia

Sao Paulo, SP, 05403-000

University of Alberta Hospital, Edmonton, Alberta, Canada

Status

Not yet recruiting

Address

University of Alberta Hospital

Edmonton, Alberta, T6G 1Z1

University of Alberta, Edmonton, Alberta, Canada

Status

Not yet recruiting

Address

University of Alberta

Edmonton, Alberta, T6G 2G3

Kelowna Respiratory and Allergy Cllinic, Kelowna, British Columbia, Canada

Status

Not yet recruiting

Address

Kelowna Respiratory and Allergy Cllinic

Kelowna, British Columbia, V1W 1V3

Vancouver, British Columbia, Canada

Status

Not yet recruiting

Address

Vancouver General Hospital; Gordon and Leslie Diamond Health Care

Vancouver, British Columbia, V5Z-1L7

Moncton, New Brunswick, Canada

Status

Not yet recruiting

Address

Clinique de pneumologie de Moncton Respiratory Clinic

Moncton, New Brunswick, E1C 2Z3

Eastern Health - General Hospital, St. John's, Newfoundland and Labrador, Canada

Status

Not yet recruiting

Address

Eastern Health - General Hospital

St. John's, Newfoundland and Labrador, A1B 3V6

Halifax, Nova Scotia, Canada

Status

Not yet recruiting

Address

Dalhousie University - Queen Elizabeth II Health Sciences Centre

Halifax, Nova Scotia, B3H 3A7

St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada

Status

Not yet recruiting

Address

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, L8N4A6

Owen Sound, Ontario, Canada

Status

Not yet recruiting

Address

Grey Bruce Health Services (GBHS) - Owen Sound Hospital

Owen Sound, Ontario,

CHUM Hôpital Notre-Dame, Montreal, Quebec, Canada

Status

Not yet recruiting

Address

CHUM Hôpital Notre-Dame

Montreal, Quebec, H2L 4M1

Montreal, Quebec, Canada

Status

Not yet recruiting

Address

McGill University, Montreal Chest Institute; Viral and other Infectious

Montreal, Quebec, H2X2P4

Beijing Hospital, Beijing City, China

Status

Not yet recruiting

Address

Beijing Hospital

Beijing City, , 100006

Beijing City, China

Status

Not yet recruiting

Address

CMU-Beijing Chao-Yang Hospital-Beijing Institute of Respiratory Medicine

Beijing City, , 100020

Beijing City, China

Status

Not yet recruiting

Address

Peking Union Medical College Hospital; Pharmacy

Beijing City, , 100730

Beijing Shi, China

Status

Not yet recruiting

Address

Beijing Friendship Hospital Affiliated of Capital University of Medical Science

Beijing Shi, , 100050

Peking University Third Hospital, Beijing, China

Status

Not yet recruiting

Address

Peking University Third Hospital

Beijing, , 100191

Ningbo First Hospital, Ningbo City, China

Status

Not yet recruiting

Address

Ningbo First Hospital

Ningbo City, , 315010

Zhongshan Hospital Fudan University, Shanghai, China

Status

Not yet recruiting

Address

Zhongshan Hospital Fudan University

Shanghai, , 200032

Shanghai, China

Status

Not yet recruiting

Address

Huadong Hospital Affiliated to Fudan University

Shanghai, , 200040

Shanghai Pulmonary Hospital, Shanghai, China

Status

Not yet recruiting

Address

Shanghai Pulmonary Hospital

Shanghai, , 200433

Shenyang City, China

Status

Not yet recruiting

Address

China Medical University (CMU) First Affiliated Hospital

Shenyang City, , 110001

Wuhan City, China

Status

Not yet recruiting

Address

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan City, , 430030

Zhengzhou Shi, China

Status

Not yet recruiting

Address

Henan University of Traditional Chinese Medicine (HUTCM) The First Affiliated Hospital

Zhengzhou Shi, ,

Brno, Czechia

Status

Not yet recruiting

Address

Fakultni nemocnice Brno; Interni hematologicka a onkologicka klinika

Brno, , 625 00

Fakultni nemocnice Olomouc, Olomouc, Czechia

Status

Not yet recruiting

Address

Fakultni nemocnice Olomouc

Olomouc, , 775 20

Plzen, Czechia

Status

Not yet recruiting

Address

Fakultni Nemocnice Plzen - Klinika Pneumologie a Ftizeologie

Plzen, , 305 99

Nemocnice Na Bulovce, Prague, Czechia

Status

Not yet recruiting

Address

Nemocnice Na Bulovce

Prague, , 180 01

Fakultni poliklinika VFN; RS centrum, Praha 2, Czechia

Status

Not yet recruiting

Address

Fakultni poliklinika VFN; RS centrum

Praha 2, , 128 08

Praha 4, Czechia

Status

Not yet recruiting

Address

Thomayerova nemocnice; Lekarna - pavilon H

Praha 4, , 140 00

Zlin, Czechia

Status

Not yet recruiting

Address

Krajska nemocnice T. Bati a.s.; Neurologicke oddeleni

Zlin, , 760 01

Aarhus Universitetshospital Skejby, Aarthus N, Denmark

Status

Not yet recruiting

Address

Aarhus Universitetshospital Skejby

Aarthus N, , 8200

Gentofte Hospital, Hellerup, Denmark

Status

Not yet recruiting

Address

Gentofte Hospital

Hellerup, , 2900

Oulu, Finland

Status

Not yet recruiting

Address

Oulun Yliopistollinen Sairaala; Teho-osasto

Oulu, , 90220

Turku University Hospital, Turku, Finland

Status

Not yet recruiting

Address

Turku University Hospital

Turku, , 20521

CHU Angers, Angers, France

Status

Not yet recruiting

Address

CHU Angers

Angers, , 49933

Hopital Avicenne, Bobigny, France

Status

Not yet recruiting

Address

Hopital Avicenne

Bobigny, , 93000

Brest, France

Status

Not yet recruiting

Address

Centre Hospitalier Regional Universitaire de Brest - Hopital de la Cavale Blanche

Brest, , 29200

Hopital Louis Pradel, Bron, France

Status

Not yet recruiting

Address

Hopital Louis Pradel

Bron, , 69677

Hospital d Instructions des Armees Percy, Clamart, France

Status

Not yet recruiting

Address

Hospital d Instructions des Armees Percy

Clamart, , 92141

Dijon, France

Status

Not yet recruiting

Address

CHU Dijon Bourgogne Hôpital François Mitterand

Dijon, , 21000

La Tronche, France

Status

Not yet recruiting

Address

CHU de Grenoble - Hôpital André Michallon; Pole Pharmacie

La Tronche, , 38700

Lille, France

Status

Not yet recruiting

Address

Centre Hospitalier Regional Universitaire de Lille

Lille, ,

Marseille, France

Status

Not yet recruiting

Address

Servie de Pneumologie et centre de Transplantation Pulmonaire

Marseille, , 13354

Montpellier, France

Status

Not yet recruiting

Address

CHU de Montpellier Hopital Arnaud de Villeneuve; de Génétique

Montpellier, , 34295

Paris, France

Status

Not yet recruiting

Address

Hopital Bichat Claude Bernard; Hepatologie Gastro Enterologie

Paris, , 75018

Paris, France

Status

Not yet recruiting

Address

European Hospital Georges Pompidou (HEGP)

Paris, , 75908

Hopital Haut Leveque, Pessac, France

Status

Not yet recruiting

Address

Hopital Haut Leveque

Pessac, , 33604

Reims, France

Status

Not yet recruiting

Address

Centre Hospitalier Universitaire de Reims; l'Hopital Maison Blanche

Reims, , 51092

Rennes, France

Status

Not yet recruiting

Address

Centre Hospitalier Universitaire de Rennes

Rennes, , 35033

Tours, France

Status

Not yet recruiting

Address

CHU Tours - Hôpital Bretonneau; Pharmacie

Tours, , 37044

Berlin, Germany

Status

Not yet recruiting

Address

Evang. Lungenklinik Berlin Klinik für Pneumologie

Berlin, , 13125

Coswig, Germany

Status

Not yet recruiting

Address

Fachkrankenhaus Coswig GmbH Zentrum f.Pneumologie Beatmungsmedizin Thorax-u.Gefäßchirurgie

Coswig, , 01640

MECS Cottbus, Cottbus, Germany

Status

Not yet recruiting

Address

MECS Cottbus

Cottbus, , 03050

Donaustauf, Germany

Status

Not yet recruiting

Address

Klinik Donaustauf Zentrum für Pneumologie

Donaustauf, , 93093

Essen, Germany

Status

Not yet recruiting

Address

Universitatsklinikum Essen; Innere Klinik

Essen, , 45122

Frankfurt am Main, Germany

Status

Not yet recruiting

Address

IFS - Interdisziplinäres Facharztzentrum; Institut für klinische Forschung Pneumologie

Frankfurt am Main, , 60596

Gießen, Germany

Status

Not yet recruiting

Address

Universitatsklinikum Gießen und Marburg GmbH

Gießen, , 35385

Hamburg, Germany

Status

Not yet recruiting

Address

Universitatsklinikum Hamburg-Eppendorf; Klinik und Poliklinik fur Neurochirurgie

Hamburg, , 20246

Hannover, Germany

Status

Not yet recruiting

Address

Fraunhofer-Institut fur Toxikologie und Experimentelle Medizin ITEM

Hannover, , 30625

Heidelberg, Germany

Status

Not yet recruiting

Address

Thoraxklinik-Heidelberg gGmbH; Apotheke der Thoraxklinik

Heidelberg, , 69120

Homburg/Saar, Germany

Status

Not yet recruiting

Address

Universitätsklinikum des Saarlandes; Klinik für Augenheilkunde

Homburg/Saar, , 66424

Lungenfachklinik Immenhausen, Immenhausen, Germany

Status

Not yet recruiting

Address

Lungenfachklinik Immenhausen

Immenhausen, , 34376

Universitatsklinikum Leipzig; Apotheke, Leipzig, Germany

Status

Not yet recruiting

Address

Universitatsklinikum Leipzig; Apotheke

Leipzig, , 04103

POIS Leipzig GbR, Leipzig, Germany

Status

Not yet recruiting

Address

POIS Leipzig GbR

Leipzig, , 04357

Mainz, Germany

Status

Not yet recruiting

Address

IKF Pneumologie Mainz Helix Medical Excellence Center Mainz

Mainz, , 55128

Mainz, Germany

Status

Not yet recruiting

Address

Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Medizinische Klinik, Pneumologie

Mainz, , 55131

Marburg, Germany

Status

Not yet recruiting

Address

Zentrum für ambulante pneumologische Forschung Marburg GbR

Marburg, , 35037

Universitaetsklinikum Muenster, Muenster, Germany

Status

Not yet recruiting

Address

Universitaetsklinikum Muenster

Muenster, , 48149

München, Germany

Status

Not yet recruiting

Address

Klinikum der Universität München - Großhadern; Apotheke

München, , 81377

Münnerstadt, Germany

Status

Not yet recruiting

Address

Lungenklinik Münnerstadt, Thoraxzentrum Bezirk Unterfranken

Münnerstadt, , 97702

Krankenhaus Bethanien gGmbH, Solingen, Germany

Status

Not yet recruiting

Address

Krankenhaus Bethanien gGmbH

Solingen, , 42699

Athens, Greece

Status

Not yet recruiting

Address

Evangelismos Hospital; Endocrinology, Diabetes & Metabolism

Athens, , 10676

Athens, Greece

Status

Not yet recruiting

Address

Laiko General Hospital of Athens; A Propedeutical Clinic of Internal Medicine

Athens, , 115 27

Athens, Greece

Status

Not yet recruiting

Address

National and Kapodistrian University of Athens EKPA Medical School

Athens, , 115 27

Athens, Greece

Status

Not yet recruiting

Address

Sotiria Hospital for Diseases of the Chest, Academic Department of Pneumonology

Athens, , 115 27

Chaidari, Greece

Status

Not yet recruiting

Address

"Attikon" University General Hospital; 3rd Department of Pediatrics

Chaidari, , 124 62

University General Hospital of Heraklion, Herakleion, Greece

Status

Not yet recruiting

Address

University General Hospital of Heraklion

Herakleion, , 711 10

Ioannina, Greece

Status

Not yet recruiting

Address

University Hospital of Ioannina; Pulmonology Department

Ioannina, , 455 00

Larisa, Greece

Status

Not yet recruiting

Address

University General Hospital of Larisa; Neurology Clinic

Larisa, , 411 10

Sotiria Athens, Greece

Status

Not yet recruiting

Address

"General hospital of Chest Diseases ""Sotiria"", 7th Pulmonary Clinic "

Sotiria Athens, , 115 27

Thessaloniki, Greece

Status

Not yet recruiting

Address

General Hospital of Thessalonikis G.Papanikolaou; Nephrology

Thessaloniki, , 570 10

Hong Kong, Hong Kong

Status

Not yet recruiting

Address

The University of Hong Kong; Queen Mary Hospital

Hong Kong, ,

Shatin, Hong Kong

Status

Not yet recruiting

Address

Prince of Wales Hosp; Dept. Of Clinical Onc

Shatin, ,

Semmelweis University, Budapest, Hungary

Status

Not yet recruiting

Address

Semmelweis University

Budapest, , 1081

Budapest, Hungary

Status

Not yet recruiting

Address

Swiss Clinic - Swiss Premium Egeszsegkozpont

Budapest, , 1123

Trial Pharma Kft, Csorna, Hungary

Status

Not yet recruiting

Address

Trial Pharma Kft

Csorna, , 9300

Debreceni Egyetem, Debrecen, Hungary

Status

Not yet recruiting

Address

Debreceni Egyetem

Debrecen, , 4032

Megyei Tudogyogyintezet - Pulmonologia, Farkasgyepu, Hungary

Status

Not yet recruiting

Address

Megyei Tudogyogyintezet - Pulmonologia

Farkasgyepu, , 8582

Miskolc, Hungary

Status

Not yet recruiting

Address

Borsod-Abauj-Zemplen (BAZ) Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz

Miskolc, ,

Szombathely, Hungary

Status

Not yet recruiting

Address

Markusovszky Egyetemi Oktatokorhaz ; SZEMESZET

Szombathely, , 9700

Törökbálint, Hungary

Status

Not yet recruiting

Address

Tudogyogyintezet Torokbalint; Onkologiai és Jarobeteg Centrum

Törökbálint, , 2045

Ashkelon, Israel

Status

Not yet recruiting

Address

Barzilai Medical Center; Neurology Department

Ashkelon, , 7830604

Shamir medical center, Be'er Ya'akov, Israel

Status

Not yet recruiting

Address

Shamir medical center

Be'er Ya'akov, , M 70300

Beer Sheva, Israel

Status

Not yet recruiting

Address

Soroka University Medical Center, Psychiatry; Psychiatry

Beer Sheva, , 8410101

Rambam Health Care Campus, Haifa, Israel

Status

Not yet recruiting

Address

Rambam Health Care Campus

Haifa, , 3109600

Haifa, Israel

Status

Not yet recruiting

Address

Bnai Zion Medical Center; Internal Medicine

Haifa, , 3339419

Haifa, Israel

Status

Not yet recruiting

Address

Carmel Medical Center; Obstetrics and Gynecology

Haifa, , 34362

Edith Wolfson Medical Center, Holon, Israel

Status

Not yet recruiting

Address

Edith Wolfson Medical Center

Holon, , 58100

Jerusalem, Israel

Status

Not yet recruiting

Address

Shaare Zedek Medical Center; Nrphrology Dept.

Jerusalem, , 91031

Hadassah Medical Center, Jerusalem, Israel

Status

Not yet recruiting

Address

Hadassah Medical Center

Jerusalem, , 9112000

Meir Medical Center, Kfar- Saba, Israel

Status

Not yet recruiting

Address

Meir Medical Center

Kfar- Saba, , 4428164

Rabin Medical Center, Petach Tiqwa, Israel

Status

Not yet recruiting

Address

Rabin Medical Center

Petach Tiqwa, , 49100

The Chaim Sheba Medical Center, Ramat Gan, Israel

Status

Not yet recruiting

Address

The Chaim Sheba Medical Center

Ramat Gan, , 5211401

Kaplan Medical Center, Rehovot, Israel

Status

Not yet recruiting

Address

Kaplan Medical Center

Rehovot, , 7610001

Tel Aviv, Israel

Status

Not yet recruiting

Address

Tel Aviv Sourasky Medical Center; Department of Neurology

Tel Aviv, , 6423906

Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Abruzzo, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Papa Giovanni XXIII

Bergamo, Abruzzo, 24060

Azienda Ospedaliera Dei Colli, Napoli, Campania, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Dei Colli

Napoli, Campania, 80131

Napoli, Campania, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Universitaria Federico II

Napoli, Campania, 80131

Napoli, Campania, Italy

Status

Not yet recruiting

Address

Università degli Studi di Napoli Federico II; Dipartimento di Scienze Oftalmologiche

Napoli, Campania, 80131

Forlì, Emilia-Romagna, Italy

Status

Not yet recruiting

Address

Ospedale Morgagni Pierantoni; Patologia clinica

Forlì, Emilia-Romagna, 47100

A.O.U. Policlinico di Modena, Modena, Emilia-Romagna, Italy

Status

Not yet recruiting

Address

A.O.U. Policlinico di Modena

Modena, Emilia-Romagna, 40124

Roma, Lazio, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera San Camillo Forlanini; Farmacia Ospedale San Camillo

Roma, Lazio, 00152

Rome, Lazio, Italy

Status

Not yet recruiting

Address

Policlinico Tor Vergata - U.O.C. Malattie Apparato Respiratorio

Rome, Lazio, 00133

Rome, Lazio, Italy

Status

Not yet recruiting

Address

Fondazione Policlinico Universitario A Gemelli; Servizio di Farmacia

Rome, Lazio, 00168

Garbagnate Milanese, Lombardia, Italy

Status

Not yet recruiting

Address

"Asst Rhodense - Unità operativa di pneumologia Ospedale ""Guido Salvini"" "

Garbagnate Milanese, Lombardia,

Milano, Lombardia, Italy

Status

Not yet recruiting

Address

Ospedale San Giuseppe; U.O. di Pneumologia

Milano, Lombardia, 20123

Asst Santi Paolo E Carlo, Milano, Lombardia, Italy

Status

Not yet recruiting

Address

Asst Santi Paolo E Carlo

Milano, Lombardia, 20142

Ospedale San Gerardo, Monza, Lombardia, Italy

Status

Not yet recruiting

Address

Ospedale San Gerardo

Monza, Lombardia, 20900

Pavia, Lombardia, Italy

Status

Not yet recruiting

Address

Fondazione IRCCS Policlinico San Matteo ; Divisione di Ematologia Dipartimento di Onco-Ematologia

Pavia, Lombardia, 27100

Torrette Di Ancona, Marche, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliero Universitaria Ospedali Riuniti

Torrette Di Ancona, Marche, 60126

Torino, Piemonte, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino; Ospedale Molinette

Torino, Piemonte, 10026

Foggia, Puglia, Italy

Status

Not yet recruiting

Address

Policlinico Riuniti di Foggia - Department of Medical and Surgical Sciences - University of Foggia

Foggia, Puglia, 71122

Sassari, Sardegna, Italy

Status

Not yet recruiting

Address

A.O.U. Sassari; Dip. Medicina Clinica e Sperimentale

Sassari, Sardegna, 07100

Catania, Sicilia, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele

Catania, Sicilia, 95123

Palermo, Sicilia, Italy

Status

Not yet recruiting

Address

Az. Osp. Univ. P. Giaccone; UOC di Pneumologia

Palermo, Sicilia, 90127

Palermo, Sicilia, Italy

Status

Not yet recruiting

Address

Ismett Istituto Mediterraneo Trapianti E Terapie Alta Specializzazione;Pneumologia

Palermo, Sicilia, 90127

Firenze, Toscana, Italy

Status

Not yet recruiting

Address

AOUC Azienda Ospedaliero-Universitaria Careggi; Neurologia 2

Firenze, Toscana, 50134

Siena, Toscana, Italy

Status

Not yet recruiting

Address

A.O. Univ. Senese Policlinico S. Maria alle Scotte; Dip. Medicina clinica e Scienze Immunologiche

Siena, Toscana, 53100

Treviso, Veneto, Italy

Status

Not yet recruiting

Address

University of Padova Ca' Foncello Hospital Immunologic & Respiratory Rare Diseases Center

Treviso, Veneto, 31100

Bucheon-si,, Korea, Republic of

Status

Not yet recruiting

Address

Soon Chun Hyang University Hospital Bucheon

Bucheon-si,, , 420-767

Gyeonggi-do, Korea, Republic of

Status

Not yet recruiting

Address

The Catholic University of Korea Bucheon St. Mary's Hospital

Gyeonggi-do, ,

Gacheon University Gil Medical Center, Namdong-gu, Korea, Republic of

Status

Not yet recruiting

Address

Gacheon University Gil Medical Center

Namdong-gu, , 21565

Seongnam-si, Korea, Republic of

Status

Not yet recruiting

Address

Seoul National University Bundang Hospital

Seongnam-si, , 13605

Samsung Medical Center, Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Samsung Medical Center

Seoul, , (0)6351

Seoul, Korea, Republic of

Status

Not yet recruiting

Address

The Catholic University of Korea Yeouido St. Mary's Hospital; Hematology-Oncology

Seoul, , (0)7345

Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Seoul National University Hospital (SNUH) - Medical Oncology Center

Seoul, , 03080

Asan Medical Center, Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Asan Medical Center

Seoul, , 05505

Korea University Guro Hospital, Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Korea University Guro Hospital

Seoul, , 08308

Seoul, Korea, Republic of

Status

Not yet recruiting

Address

The Catholic University of Korea Seoul St. Mary's Hospital

Seoul, , 137-701

Soonchunhyang University Hospital, Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Soonchunhyang University Hospital

Seoul, ,

San Nicolás de Los Garza, Nuevo LEON, Mexico

Status

Not yet recruiting

Address

Unidad Médica para la Salud Integral UMSI

San Nicolás de Los Garza, Nuevo LEON, 66465

Unidad de Investigacion CIMA SC, Chihuahua, Mexico

Status

Not yet recruiting

Address

Unidad de Investigacion CIMA SC

Chihuahua, , 31200

Metepec, Mexico

Status

Not yet recruiting

Address

Centro de Diagnóstico y Tratamiento de Enfermedades Respiratorias, Medica San Isidro

Metepec, , 52140

Centro Respiratorio de México, Mexico, Mexico

Status

Not yet recruiting

Address

Centro Respiratorio de México

Mexico, , 14050

Mexico, Mexico

Status

Not yet recruiting

Address

INER- Instituto Nacional de Enfermedades Respiratorias"Ismae

Mexico, , 14080

Monterrey, Mexico

Status

Not yet recruiting

Address

Hospital Uni Dr. Jose E. Gonzalez; Centro Regional de Prevencion Y Diagnostico de Osteoporosis

Monterrey, , 64460

Monterrey, Mexico

Status

Not yet recruiting

Address

Unidad de Investigacion Clinica En Medicina (Udicem) S.C.

Monterrey, , 64718

CICC Morelia, Morelia, Mexico

Status

Not yet recruiting

Address

CICC Morelia

Morelia, ,

Centro Médico Toluca ISSEMYM, Toluca, Mexico

Status

Not yet recruiting

Address

Centro Médico Toluca ISSEMYM

Toluca, , 52710

VU Medisch Centrum, Amsterdam, Netherlands

Status

Not yet recruiting

Address

VU Medisch Centrum

Amsterdam, , 1081 HV

LUMC, Leiden, Netherlands

Status

Not yet recruiting

Address

LUMC

Leiden, , 2300 ZA

Nieuwegein, Netherlands

Status

Not yet recruiting

Address

Sint Antonius Ziekenhuis, locatie Nieuwegein

Nieuwegein, , 3430 EM

Erasmus Medisch Centrum, Rotterdam, Netherlands

Status

Not yet recruiting

Address

Erasmus Medisch Centrum

Rotterdam, , 3000 CA

Haaglanden Medisch Centrum Westeinde, Zuid-Holland, Netherlands

Status

Not yet recruiting

Address

Haaglanden Medisch Centrum Westeinde

Zuid-Holland, ,

Auckland City Hospital, Auckland, New Zealand

Status

Not yet recruiting

Address

Auckland City Hospital

Auckland, , 1023

NZ Respiratory & Sleep Institute, Auckland, New Zealand

Status

Not yet recruiting

Address

NZ Respiratory & Sleep Institute

Auckland, , 1051

University of Otago, Christchurch, Christchurch, New Zealand

Status

Not yet recruiting

Address

University of Otago, Christchurch

Christchurch, , 8011

Otago Respiratory Research Unit, Dunedin, New Zealand

Status

Not yet recruiting

Address

Otago Respiratory Research Unit

Dunedin, , 9054

Waikato Hospital; Gastro Research, Hamilton, New Zealand

Status

Not yet recruiting

Address

Waikato Hospital; Gastro Research

Hamilton, , 3240

Tauranga Hospital, Tauranga, New Zealand

Status

Not yet recruiting

Address

Tauranga Hospital

Tauranga, , 3143

Arendal, Norway

Status

Not yet recruiting

Address

Soerlandet Sykehus Arendal; Medisinsk Avdeling

Arendal, , 4838

Akershus universitetssykehus, Lørenskog, Norway

Status

Not yet recruiting

Address

Akershus universitetssykehus

Lørenskog, , 1478

Oslo, Norway

Status

Not yet recruiting

Address

Oslo University Hospital HF, Rikshospitalet

Oslo, , 0424

Hospital de Chancay, Chancay, Peru

Status

Not yet recruiting

Address

Hospital de Chancay

Chancay, , 15131

Jesús María, Peru

Status

Not yet recruiting

Address

Hospital Militar Central del Ejercito del Perú

Jesús María, , 15082

La Victoria, Peru

Status

Not yet recruiting

Address

Hospital Guillermo Almenara Irigoyen Hospital Guillermo Almenara Irigoyen Hospital Guillermo Almen

La Victoria, , Lima 13

Lima, Peru

Status

Not yet recruiting

Address

Clinica San Borja; Servicio De Reumatologia

Lima, , 15036

Clinica Delgado, Lima, Peru

Status

Not yet recruiting

Address

Clinica Delgado

Lima, , 15074

Hospital Nacional Cayetano Heredia, Lima, Peru

Status

Not yet recruiting

Address

Hospital Nacional Cayetano Heredia

Lima, , 31

Clinica San Pablo, Lima, Peru

Status

Not yet recruiting

Address

Clinica San Pablo

Lima, , Lima 33

Hospital Central FAP, Miraflores, Peru

Status

Not yet recruiting

Address

Hospital Central FAP

Miraflores, , 15046

Piura, Peru

Status

Not yet recruiting

Address

Centro de Investigacion en Reumatologia de la Clinica Belen

Piura, ,

Clinica Internacional - Sede San Borja, San Borja, Peru

Status

Not yet recruiting

Address

Clinica Internacional - Sede San Borja

San Borja, , 15036

Centrum Medycyny Oddechowej Mroz sp. j., Białystok, Poland

Status

Not yet recruiting

Address

Centrum Medycyny Oddechowej Mroz sp. j.

Białystok, , 15-044

Nasz Lekarz Osrodek Badan Klinicznych, Bydgoszcz, Poland

Status

Not yet recruiting

Address

Nasz Lekarz Osrodek Badan Klinicznych

Bydgoszcz, , 85-312

Grudziadz, Poland

Status

Not yet recruiting

Address

Prywatny Gabinet Pulmonologiczny Joanna Nowacka-Apiyo

Grudziadz, , 86-300

Gornoslaskie Centrum Medyczne, Katowice, Poland

Status

Not yet recruiting

Address

Gornoslaskie Centrum Medyczne

Katowice, , 40-635

Jagiellonskie Centrum Innowacji, Kraków, Poland

Status

Not yet recruiting

Address

Jagiellonskie Centrum Innowacji

Kraków, , 30-348

Lodz, Poland

Status

Not yet recruiting

Address

Uniwersytecki Szpital Kliniczny Nr 1 im.N.Barlickiego Oddzial Kliniczny Pneumonologii i Alergologii

Lodz, , 90-153

Lublin, Poland

Status

Not yet recruiting

Address

MS Clinsearch Specjalistyczny NZOZ Janusz Milanowski Katarzyna Szmygin-Milanowska Spółka Jawna

Lublin, , 02-090

Sosnowiec, Poland

Status

Not yet recruiting

Address

PULMAG Arkadiusz Brodowski, Grzegorz Gasior S. C.

Sosnowiec, , 41-200

Warszawa, Poland

Status

Not yet recruiting

Address

Instytut Gruzlicy i Chorob Pluc; Apteka Zakladowa

Warszawa, , 01-138

Centrum Badań Klinicznych, Wrocław, Poland

Status

Not yet recruiting

Address

Centrum Badań Klinicznych

Wrocław, , 51-162

Zabrze, Poland

Status

Not yet recruiting

Address

Samodzielny Publiczny Szpital Kliniczny nr 1

Zabrze, , 44803

Braga, Portugal

Status

Not yet recruiting

Address

Hospital de Braga; Centro Clínico Académico (Piso 1, Ala E)

Braga, , 4710-243

Centro Hospitalar Algarve, Faro, Portugal

Status

Not yet recruiting

Address

Centro Hospitalar Algarve

Faro, , 8000-386

Guimaraes, Portugal

Status

Not yet recruiting

Address

Hospital Senhora da Oliveira - Guimarses, E.P.E

Guimaraes, , 4835-044

Lisboa, Portugal

Status

Not yet recruiting

Address

Centro Hospitalar Universitario Lisboa Norte - Hospital Pulido Valente

Lisboa, , 1769-001

Porto, Portugal

Status

Not yet recruiting

Address

Centro Hospitalar do Porto - Hospital de Santo António

Porto, , 4099-001

Porto, Portugal

Status

Not yet recruiting

Address

Hospital de Sao Joao; Centro de Investigacao

Porto, , 4200-319

Hospital de Santa Luzia, Porto, Portugal

Status

Not yet recruiting

Address

Hospital de Santa Luzia

Porto, ,

Vila Nova De Gaia, Portugal

Status

Not yet recruiting

Address

CHVNG/E_Unidade 1; Servico de Pneumologia

Vila Nova De Gaia, , 4434-502

Barnaul, Altaj, Russian Federation

Status

Not yet recruiting

Address

Regional State Budgetary Institution of Healthcare "Regional Clinical Hospital"

Barnaul, Altaj, 656024

Moscow, Moskovskaja Oblast, Russian Federation

Status

Not yet recruiting

Address

Moscow State Medical and Dental University n. a. A.I. Evdokimova

Moscow, Moskovskaja Oblast, 127473

Moscow, Moskovskaja Oblast, Russian Federation

Status

Not yet recruiting

Address

National Medical Research Center for Phthisiopulmonology and Infectious Diseases

Moscow, Moskovskaja Oblast, 127473

Central NII tuberkuleza RAMN, Moscow, Moskovskaja Oblast, Russian Federation

Status

Not yet recruiting

Address

Central NII tuberkuleza RAMN

Moscow, Moskovskaja Oblast,

Moscow, Moskovskaja Oblast, Russian Federation

Status

Not yet recruiting

Address

SBEI HPE "The First Moscow State Medical University n.a. I. M. Sechenov Health Ministry of RF

Moscow, Moskovskaja Oblast,

City Outpatients' clinic #25, Sankt-peterburg, Sankt Petersburg, Russian Federation

Status

Not yet recruiting

Address

City Outpatients' clinic #25

Sankt-peterburg, Sankt Petersburg, 193312

Energia Zdorovia, LLC, St. Petersburg, Sankt Petersburg, Russian Federation

Status

Not yet recruiting

Address

Energia Zdorovia, LLC

St. Petersburg, Sankt Petersburg,

Pyatigorsk, Stavropol, Russian Federation

Status

Not yet recruiting

Address

SBHI of Stavropol region "City Hospital #2" of Pyatigorsk

Pyatigorsk, Stavropol, 357538

Izhevsk, Udmurtija, Russian Federation

Status

Not yet recruiting

Address

City Clinical Hospital No. 9 of the Ministry of Health of the Udmurt Republic

Izhevsk, Udmurtija, 426063

Regional clinical hospital #3, Chelyabinsk, Russian Federation

Status

Not yet recruiting

Address

Regional clinical hospital #3

Chelyabinsk, , 454021

Chelyabinsk, Russian Federation

Status

Not yet recruiting

Address

Chelyabinsk Regional Clinical Hospital; Hematology

Chelyabinsk, , 454076

Petrozavodsk, Russian Federation

Status

Not yet recruiting

Address

Republican Hospital Named After V.A. Baranov

Petrozavodsk, , 185019

Sankt Peterburg, Russian Federation

Status

Not yet recruiting

Address

State Budgetary Educational Institution of Higher Professional Education

Sankt Peterburg, , 197022

Vladimir, Russian Federation

Status

Not yet recruiting

Address

SBIH at Vladimir Region "Regional Clinical Hospital"

Vladimir, , 600023

National University Hospital, Singapore, Singapore

Status

Not yet recruiting

Address

National University Hospital

Singapore, , 119074

Singapore General Hospital, Singapore, Singapore

Status

Not yet recruiting

Address

Singapore General Hospital

Singapore, , 169608

Tan Tock Seng Hospital, Singapore, Singapore

Status

Not yet recruiting

Address

Tan Tock Seng Hospital

Singapore, , 308433

Cape Town, South Africa

Status

Not yet recruiting

Address

University of Cape Town Lung Institute; Lung Clinical Research

Cape Town, , 7700

Johese Clinical Research, Centurion, South Africa

Status

Not yet recruiting

Address

Johese Clinical Research

Centurion, , 1692

Groenkloof, South Africa

Status

Not yet recruiting

Address

Into Research; Life Groenkloof Hospital Medical Centre

Groenkloof, , 0181

Vergelegen Medi-Clinic, Somerset West, South Africa

Status

Not yet recruiting

Address

Vergelegen Medi-Clinic

Somerset West, , 7130

HUA - Txagorritxu, Vitoria, Alava, Spain

Status

Not yet recruiting

Address

HUA - Txagorritxu

Vitoria, Alava, 1009

Hospital Universitari de Bellvitge, L'hospitalet de Llobregat, Barcelona, Spain

Status

Not yet recruiting

Address

Hospital Universitari de Bellvitge

L'hospitalet de Llobregat, Barcelona, 08907

Sabadell, Barcelona, Spain

Status

Not yet recruiting

Address

Corporació Sanitaria Parc Taulí; Servicio de Neurología

Sabadell, Barcelona, 08208

Santander, Cantabria, Spain

Status

Not yet recruiting

Address

Hospital Universitario Marques de Valdecilla

Santander, Cantabria, 39008

Hospital Universitari Son Espases, Palma de Mallorca, Islas Baleares, Spain

Status

Not yet recruiting

Address

Hospital Universitari Son Espases

Palma de Mallorca, Islas Baleares, 07120

CHUS - H. Clinico U. de Santiago, Santiago de Compostela, LA Coruña, Spain

Status

Not yet recruiting

Address

CHUS - H. Clinico U. de Santiago

Santiago de Compostela, LA Coruña, 15706

Hospital Universitario del Henares, Coslada, Madrid, Spain

Status

Not yet recruiting

Address

Hospital Universitario del Henares

Coslada, Madrid, 28850

Majadahonda, Madrid, Spain

Status

Not yet recruiting

Address

Hospital Universitario Puerta de Hierro - Majadahonda

Majadahonda, Madrid, 28220

Pozuelo de Alarcón, Madrid, Spain

Status

Not yet recruiting

Address

Hospital Universitario Quironsalud Madrid

Pozuelo de Alarcón, Madrid, 28223

Pamplona, Navarra, Spain

Status

Not yet recruiting

Address

Universidad de Navarra - Clinica Universitaria de Navarra (CUN)

Pamplona, Navarra, 31008

Hospital Galdakao-Usansolo, Galdakao, Vizcaya, Spain

Status

Not yet recruiting

Address

Hospital Galdakao-Usansolo

Galdakao, Vizcaya, 48960

Barcelona, Spain

Status

Not yet recruiting

Address

Hospital de la Santa Creu i Sant Pau; Servicio de Neumologia

Barcelona, , 08025

Barcelona, Spain

Status

Not yet recruiting

Address

Hospital Univ Vall d'Hebron; Servicio de Oncologia

Barcelona, , 08035

Hospital Clinic de Barcelona, Barcelona, Spain

Status

Not yet recruiting

Address

Hospital Clinic de Barcelona

Barcelona, , 08036

Hospital Germans Trias i Pujol, Barcelona, Spain

Status

Not yet recruiting

Address

Hospital Germans Trias i Pujol

Barcelona, , 08916

Granada, Spain

Status

Not yet recruiting

Address

Hospital Virgen de las Nieves; Servicio de Neumologia

Granada, , 18014

Madrid, Spain

Status

Not yet recruiting

Address

Hospital Universitario de La Princesa; Aparato Digestivo

Madrid, , 28006

Madrid, Spain

Status

Not yet recruiting

Address

Clínica Universidad de Navarra; Servicio de Farmacia

Madrid, , 28027

Madrid, Spain

Status

Not yet recruiting

Address

Hospital Ramón y Cajal;Servicio de Neumología

Madrid, , 28034

Madrid, Spain

Status

Not yet recruiting

Address

Hospital Clinico San Carlos; Servicio de Farmacia

Madrid, , 28040

Hospital Universitario 12 de Octubre, Madrid, Spain

Status

Not yet recruiting

Address

Hospital Universitario 12 de Octubre

Madrid, , 28041

Salamanca, Spain

Status

Not yet recruiting

Address

Hospital Clinico Universitario de Salamanca

Salamanca, , 37007

CEIC del Hospital Virgen del Rocío, Sevilla, Spain

Status

Not yet recruiting

Address

CEIC del Hospital Virgen del Rocío

Sevilla, , 41013

Valencia, Spain

Status

Not yet recruiting

Address

Hospital Clinico Universitario de Valencia

Valencia, , 46010

Valencia, Spain

Status

Not yet recruiting

Address

Hospital Universitari i Politecnic La Fe de Valencia

Valencia, , 46026

Sahlgrenska Universitetssjukhuset, Goteborg, Sweden

Status

Not yet recruiting

Address

Sahlgrenska Universitetssjukhuset

Goteborg, , 413 45

Karolinska University Hospital, Stockholm, Sweden

Status

Not yet recruiting

Address

Karolinska University Hospital

Stockholm, , 171 76

Uppsala, Sweden

Status

Not yet recruiting

Address

Uppsala Universitet - Akademiska Sjukhuset

Uppsala, , 752 37

Universitaetsspital Basel, Basel, Switzerland

Status

Not yet recruiting

Address

Universitaetsspital Basel

Basel, , 4031

Universitatsspital Bern, Bern, Switzerland

Status

Not yet recruiting

Address

Universitatsspital Bern

Bern, , 3010

Lausanne, Switzerland

Status

Not yet recruiting

Address

Centre Hospitalier Universitaire Vaudois (CHUV) ; Département d'Oncologie médicale - BH09 - Bureau 7

Lausanne, , 1011

Neuchâtel, Switzerland

Status

Not yet recruiting

Address

Hopital Neuchatelois Pourtales (Hopitaux Cadolles Pourtales)

Neuchâtel, , 2000

Chia-yi, Taiwan

Status

Not yet recruiting

Address

Buddhist Tzu Chi Dalin General Hospital; Rheumatology

Chia-yi, , 622

Kaoshiung City, Taiwan

Status

Not yet recruiting

Address

Kaohsiung Medical University Hospital; Chung-Ho Memorial Hospital

Kaoshiung City, , 807

China Medical University Hospital, Taichung, Taiwan

Status

Not yet recruiting

Address

China Medical University Hospital

Taichung, , 40447

National Cheng Kung University Hospital, Tainan, Taiwan

Status

Not yet recruiting

Address

National Cheng Kung University Hospital

Tainan, , 70457

National Taiwan University Hospital, Taipei, Taiwan

Status

Not yet recruiting

Address

National Taiwan University Hospital

Taipei, , 10002

Taipei, Taiwan

Status

Not yet recruiting

Address

Far Eastern Memorial Hospital; Department of Clinical Pathology

Taipei, , 220

Veterans General Hospital - Taichung, Xitun Dist., Taiwan

Status

Not yet recruiting

Address

Veterans General Hospital - Taichung

Xitun Dist., , 40705

Adana, Turkey

Status

Not yet recruiting

Address

Cukurova Universitesi Tip Fakultesi Balcali Hastanesi; Balcali; Onkologi

Adana, , 01330

Ankara, Turkey

Status

Not yet recruiting

Address

Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi

Ankara, ,

Bursa, Turkey

Status

Not yet recruiting

Address

Uludag Universitesi - Saglik Uygulama ve Arastirrma Merkezi

Bursa, , 16059

Gaziantep Universitesi Tip Fakultesi, Gaziantep, Turkey

Status

Not yet recruiting

Address

Gaziantep Universitesi Tip Fakultesi

Gaziantep, , 27310

Istanbul, Turkey

Status

Not yet recruiting

Address

Yedikule Gogus Hastaliklari ve Gogus Cerrahisi EAH;Gogus Hastaliklari

Istanbul, , 34020

İstanbul, Turkey

Status

Not yet recruiting

Address

Istanbul Universitesi Onkoloji Enstitüsü Hastanesi

İstanbul, , 34093

Ege Universitesi Tip Fakultesi Hastanesi, Izmir, Turkey

Status

Not yet recruiting

Address

Ege Universitesi Tip Fakultesi Hastanesi

Izmir, , 35100

Izmir, Turkey

Status

Not yet recruiting

Address

Dokuz Eylul University Faculty of Medicine; Chest Diseases

Izmir, , 35340

Kocaeli Universitesi Tip Fakultesi, Kocaeli, Turkey

Status

Not yet recruiting

Address

Kocaeli Universitesi Tip Fakultesi

Kocaeli, , 41380

Melikgazi/Kayser, Turkey

Status

Not yet recruiting

Address

Eriyes universitesi Tıp Fakultesi Hastanesi

Melikgazi/Kayser, , 38039

Mersin, Turkey

Status

Not yet recruiting

Address

Mersin Universitesi Tip Fakultesi Hastanesi; Tibbi Onkoloji Birimi

Mersin, , 33343

Muratpasa/Antalya, Turkey

Status

Not yet recruiting

Address

Akdeniz University Faculty of Medicine Department of Pulmonology

Muratpasa/Antalya, , 07059

Sariyer, Turkey

Status

Not yet recruiting

Address

Koc Universitesi (KU) Tip Fakultesi (Koc University School of Medicine)

Sariyer, , 34450

Ueskuedar, Turkey

Status

Not yet recruiting

Address

Marmara Universitesi Hastanesi Marmara University Hospital

Ueskuedar, ,

Dnipro, Katerynoslav Governorate, Ukraine

Status

Not yet recruiting

Address

Municipal Non-Profit Enterprise City Clinical Hospital #16 of Dnipro City Council

Dnipro, Katerynoslav Governorate, 49069

Kyiv, KIEV Governorate, Ukraine

Status

Not yet recruiting

Address

National Academy of Medical Science of Ukraine (NAMS); NRCRM

Kyiv, KIEV Governorate, 3115

CHI Kharkiv City Clinical Hospital #13, Kharkiv, Ukraine

Status

Not yet recruiting

Address

CHI Kharkiv City Clinical Hospital #13

Kharkiv, , 61124

Kyiv, Ukraine

Status

Not yet recruiting

Address

Yanovskyy Inst of Phth. & Pulm; Clinical-functional

Kyiv, , 03680

Odessa regional clinical Hospital, Odessa, Ukraine

Status

Not yet recruiting

Address

Odessa regional clinical Hospital

Odessa, , 65117

Edinburgh, United Kingdom

Status

Not yet recruiting

Address

Edinburgh Royal Infirmary; Respiratory Department

Edinburgh, , EH16 4SA

Exeter, United Kingdom

Status

Not yet recruiting

Address

Royal Devon & Exeter Hospital; Cardiology Department

Exeter, , EX2 5DW

Forth Valley Royal Hospital, Larbert, United Kingdom

Status

Not yet recruiting

Address

Forth Valley Royal Hospital

Larbert, , FK5 4WR

Glenfield Hospital, Leicester, United Kingdom

Status

Not yet recruiting

Address

Glenfield Hospital

Leicester, , LE3 9QP

London, United Kingdom

Status

Not yet recruiting

Address

University College London Hospital; Respiratory Medicine

London, , NW1 2BU

London, United Kingdom

Status

Not yet recruiting

Address

Guys and St Thomas NHS Foundation Trust, Guys Hospital

London, , SE1 9RT

North Manchester General Hospital, Manchester, United Kingdom

Status

Not yet recruiting

Address

North Manchester General Hospital

Manchester, , M8 5RB

Queen Alexandra Hospital, Portsmouth, Portsmouth, United Kingdom

Status

Not yet recruiting

Address

Queen Alexandra Hospital, Portsmouth

Portsmouth, , PO6 3LY

South Shields, United Kingdom

Status

Not yet recruiting

Address

South Tyneside and Sunderland NHS Foundation trust

South Shields, , NE34 0PL

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